Lou Gehrig’s syndrome: Here are the first symptoms of this disease

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## 8. Progressive Muscle Wasting

When motor neurons no longer stimulate muscles normally, the affected muscles may gradually shrink.

 

 

This is called **muscle atrophy**.

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You might notice:

* One hand looking thinner than the other
* Reduced muscle bulk in an arm or leg
* Increasing weakness in the same area
* Clothes fitting differently because a limb has become thinner

Muscle wasting alongside weakness and twitching is one of the neurological patterns clinicians evaluate when considering ALS. ([Mayo Clinic][2])

 

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## 9. Muscle Stiffness

ALS can also cause increased muscle tone or stiffness.

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A person may feel that:

* Legs are unusually tight
* Movements are harder to initiate
* Walking feels stiff or awkward
* Muscles jerk unexpectedly

 

 

Neurologists refer to this type of increased muscle stiffness as spasticity.

## 10. Changes in Emotional Expression

Some people with ALS develop episodes of laughing or crying that seem exaggerated or inappropriate for the situation.

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