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Within just 48 hours of switching to a new inhaler, a 55-year-old woman developed painful, bright red patches across her face and neck, accompanied by a mild fever. What initially looked like a simple skin reaction after a routine COPD treatment change was later found to be a rare immune condition known as Sweet syndrome.

The 55-year-old patient had a history of COPD and hypertension, previously stable on long-term medication. Due to worsening lung function, her inhaler was changed to a combination of indacaterol and glycopyrronium, a commonly used therapy designed to improve airflow. The adjustment was considered routine and generally safe.

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